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The Pharmaceutical Journal Vol 263 No 7069 p710
October 30, 1999 Letters

Buprenorphine

Caution

From Mr A. R. L. Buxton, MRPharmS

SIR,—I am writing to draw to the attention of all pharmacists the potential for confusion in the writing of prescriptions for oral buprenorphine.
I was recently called upon to dispense a prescription for buprenorphine 2mg tablets (Subutex, Schering-Plough), a product indicated as substitution treatment for opioid drug dependence. The prescriber intended that the patient should receive buprenorphine 200µg tablets (Temgesic, Schering-Plough) for analgesia. This simple prescribing error could have led to the patient receiving 10 times the dose of drug intended.
I would recommend that pharmacists are particularly vigilant when called upon to dispense Subutex in the community, especially if it has been prescribed generically.

Alastair Buxton
Shrewsbury