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The Pharmaceutical Journal Vol 265 No 7119 p629
October 21, 2000 International

World congress of pharmacy

Is the effect of volatile oils all in the mind?

Professor Gerhard Buchbauer (Vienna, Austria) continued the theme of the pharmacological basis of claims made for efficacy of volatile oils. He emphasised the difference between aromatherapy, in which a distinct physical effect could be observed, and aromachology, where the effect was, at least to some extent, a psychological reaction to the odour of the essential oil. The two were often connected, such as when a good feeling, induced by a pleasant smell, resulted in a general relaxation of muscles. He also cited studies showing that effects were often related to expectations.
There was, however, some evidence for a direct therapeutic effect, and in some cases the constituents responsible had been isolated and shown to have comparable activity. Thus the sleep-inducing properties of hop pillows had been shown to be due to 2-methyl-3-buten-2-ol, while 1,8-cineole in rosemary oil had been shown to increase motor activity and blood supply to the central nervous system, revealed by xenon radiodiagnosis computer-aided tomography of patients.
Conversely, linalool from lavender oil showed a decrease in activity, particularly after the animals tested had been over-agitated by a dose of caffeine. Stress and travel-sickness in pigs had been reduced by using lavender straw for their bedding while in transit.
Professor Buchbauer also quoted work that had shown that repeated massage with oil had resulted in an accumulation in the tissues. Limonene had a half-life of 54 hours, so there was the possibility of toxic doses in the bloodstream being reached if frequent massage with oils containing this terpene occurred.