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The Pharmaceutical Journal Vol 265 No 7120 p644
October 28, 2000 Clinical

Sildenafil use in infertile women criticised

The use of sildenafil (Viagra) in infertile women to assist conception has been criticised by a leading gynaecologist.
Professor Lord Robert Winston (head of reproductive medicine, Hammersmith hospital, London), whose comments appear in national newspaper reports, says that sildenafil is unlikely to be of any benefit to infertile women and that its use in women hoping to conceive or in the early stages of pregnancy is irresponsible.
A spokeswoman for Pfizer, the manufacturer of the drug, told The Journal on October 24 that the use of sildenafil in the treatment of infertility was outside the drug’s product labelling and Pfizer was, therefore, not in a position to recommend its use in such cases. She added that Pfizer had not conducted any trials to study the effects of sildenafil in infertile women but that this might be a possibility for the future. Trials to study the efficacy of the drug in the treatment of female sexual dysfunction were under way but results were still at a preliminary stage, she said. Sildenafil is currently indicated for treatment of erectile dysfunction only.