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The Pharmaceutical Journal Vol 267 No 7156 p39-44
July 14, 2001

News summary


Decline in MMR vaccinations

The number of children vaccinated with the MMR (measles, mumps and rubella) vaccine in the United Kingdom has declined.

The Public Health Laboratories Service attributes the decrease to the implementation of the meningitis C vaccination programme rather than to adverse publicity about MMR.

In the first quarter of this year, 86.4 per cent of children were vaccinated by the age of 24 months, which represents a 1.6 per cent drop compared with the previous three months. The reduction was similar for all countries within the UK.

The PHLS says that MMR vaccine was being offered at the same time that children were being given catch-up doses of meningitis C vaccine, which might have resulted in children only receiving one of the two vaccines. The uniformity of the drop throughout the UK supports the theory that the reduction was caused by pressure put upon primary care services by offering the two vaccines at the same time. Previous adverse publicity about MMR vaccine had not resulted in a uniform drop, the PHLS says.

A spokeswoman for the PHLS told The Journal that the reduction might go on for another six months, while the two vaccines were offered together, but that numbers should increase again when all children had been given a catch-up dose of meningitis C vaccine.

To maintain “herd” immunity, a 95 per cent uptake of MMR vaccine is required.

Concern over the safety of yellow-fever vaccination has been raised in two articles and one research letter in this week’s issue of The Lancet (2001;358:84, 91, 98 and 121). Seven severe reactions, including six deaths, after vaccination are described in the studies.

However, the authors conclude that despite the concerns, yellow-fever vaccination programmes should be continued.

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