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The Pharmaceutical Journal Vol 267 No 7170 p537-541
20 October 2001

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Patients suffering MIs without chest pain not treated optimally

Failure to use beneficial treatment strategies for myocardial infarction (MI) for patients presenting without chest pain could be a reason for the poor prognosis associated with this form of acute MI. This is the conclusion of Dr Mischa Dorsch and colleagues of the British Heart Foundation Heart Research Centre, Leeds General Infirmary.

The researchers reviewed the medical notes of patients with suspected MIs and confirmed 2,096 consecutive cases over a three-month period. The mortality rate at both 30 and 365 days post-MI was higher for patients presenting without chest pain than for patients presenting with chest pain. The researchers say that this can partly be explained by the higher risk factor profile of patients presenting without chest pain (they were older and more likely to have a history of congestive heart failure). However, these patients were less likely to be managed within coronary care units or to be discharged from hospital with prescriptions for aspirin and beta-blockers.

Because some patients are not diagnosed with MI on admission, they may not be admitted to coronary care units. However, this does not explain the failure to discharge patients with appropriate treatment, as diagnosis has been confirmed at this stage. “Reasons for this may include preferential focus on symptomatic rather than prognostic treatment strategies,” they say.

The researchers conclude that implementation of the National Service Framework for Coronary Heart Disease should improve the care of these patients (Heart 2001;86:494).

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