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The Pharmaceutical Journal Vol 267 No 7173 p667-671
10 November 2001

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Vitamin D reduces risk of diabetes

Vitamin D supplementation in children reduces the risk of developing type 1 diabetes, reseachers say.

Dr Elina Hyppönen, Institute of Child Health, London, and colleagues investigated the incidence of type 1 diabetes in 10,366 children in Finland. Frequency and dose of vitamin D supplementation was recorded from birth and the primary outcome was incidence of type 1 diabetes.

Children who took vitamin D supplements had a lower incidence of type 1 diabetes than those who did not, irrespective of the dose taken. In children who regularly took the recommended dose of vitamin D (2,000IU daily), the risk of developing type 1 diabetes was reduced by about 80 per cent compared with those who took less. “We believe that vitamin D might somehow inhibit the autoimmune reaction targeted towards the beta cells of the pancreas,” the authors comment.

However, they caution that because vitamin D is potentially toxic, care should be taken over changing recommendations about intake. (Lancet 2001;358:1500).

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