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The Pharmaceutical Journal
Vol 268 No 7181 p45-49
19 January 2002

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MeReC Bulletin tackles management of osteoporosis

The latest issue of the MeReC Bulletin considers issues surrounding the management of osteoporosis, including the treatment of men with osteoporosis and the treatment of corticosteroid-induced osteoarthritis (2001;12:5).

The bulletin concludes that there is little evidence to help determine the best drug treatment for osteoarthritis in men but says that there is no suggestion that men should respond to treatment any differently from women. It says that there is some evidence that the bisphosphonates etidronate and alendronate can increase bone mineral density in men and that a combination of calcium and vitamin D may be of benefit in older men.

For corticosteroid-induced osteoporosis, the bulletin recommends that bisphosphonates are used first. It adds that hormone replacement therapy (HRT) might be appropriate for women who do not tolerate bisphosphonates but notes that there is little evidence to suggest that HRT affects fracture rates. Other issues considered by the bulletin include the measurement and interpretation of bone mineral density and the prevention of falls.

The bulletin is included with The Journal sent to pharmacists in England and Wales this week.

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