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The Pharmaceutical Journal
Vol 268 No 7183 p123-130
2 February 2002


News summary

Research and Development   News in brief

Control of entry article leads to three hour OFT grilling for Day Lewis boss
Kirit Patel, chairman of the Day Lewis group of pharmacies, spent three hours talking to the Office of Fair Trading last week as part of its investigation into control of entry...[more]

ETP pilots head towards intensive beta-testing stage The three pilot schemes for electronic transmission of prescriptions (ETP) are all heading towards more intensive beta-testing (the second stage of testing new software, involving selected users in normal operating conditions) of their systems despite software development problems and the withdrawal of another member from the TransScript consortium...[more]

Supplies of dressings are taken off prescription in Isle of Wight pilots Isle of Wight Primary Care Trust is piloting a new way of supplying dressings through community pharmacies without the need for a doctor's prescription...[more]

Pharmacists to sell prepayment certificates under Scottish scheme Patients will be able to buy prepayment certificates direct from community pharmacists in Scotland from April...[more]

Community technician completes prescription checking course Teresa Bevan has become the first community pharmacy technician to complete the dispensing technician checking course that results in a nationally recognised qualification...[more]

Look what you could lose, say south London pharmacies Pharmacy customers in Lambeth, Southwark and Lewisham, south London, are to be warned that they may lose free services...[more]

MCA seeks information on Epilim in pregnancy The Medicines Control Agency wants new data on the use of sodium valproate (Epilim) in pregnant women and will be seeking advice from the Committee on Safety of Medicines when the data becomes available...[more]

NICE defends its work to the Health Select Committee The National Institute for Clinical Excellence has given the House of Commons Health Select Committee a comprehensive defence of its work so far...[more]

NICE panel rejects MS appeals A National Institute of Clinical Excellence appeal panel has rejected all arguments brought against the institute's final determination on the use of beta interferon and glatiramer acetate in multiple sclerosis...[more]

Lords challenge on robotic dispensing A challenge to the Government to draw up a national specification for robotic dispensing has been issued in the House of Lords...[more]

Benefits of adding rituximab confirmed Adding rituximab (MabThera) to the standard treatment for patients with diffuse large-B-cell lymphoma results in an increased complete-response rate and prolongs event-free and overall survival, a new study confirms...[more]

Europe proposes registration procedure for herbal medicines A specific registration procedure for herbal medicines with long-standing traditional use has been proposed by the European Commission...[more]

Safety concerns over butterbur Pharmacists should advise patients not to purchase crude butterbur from herbalists, according to expert opinion...[more]

Incidence of gastric 'flu not unusual, says PHLS The number of cases of gastric 'flu, which have been widely reported in the national media, does not appear to be out of proportion to those seen in previous winters, says the Public Health Laboratory Service...[more]

Two-step peroxide system performs best in contact lens solution study A study designed to test three contact lens solutions has concluded that a two-step peroxide system (0.6 per cent hydrogen peroxide) has better amoebicidal properties than a one step peroxide system (3 per cent) or a multipurpose disinfecting solution...[more]

Povidone-iodine for impetigo not supported by study results Use of povidone-iodine alone or as an adjunctive treatment for impetigo is of questionable value, say Dutch researchers...[more]

Cidex disinfectant to be withdrawn Cidex (glutaraldehyde), a disinfecting agent widely used in hospitals for disinfecting medical instruments, is being withdrawn from the market...[more]

Free NHS from political control, says King's Fund Politicians should not be closely involved with decision-making in the National Health Service, says a King's Fund report...[more]

Ambulance service tells patients: "Talk to a pharmacist" London Ambulance Service is telling people to seek advice from pharmacists about non-emergency medical advice or treatment as part of a campaign to reduce inappropriate use of ambulances...[more]

Transparency needed for approving new local pharmaceutical services There is insufficient detail on the process for approving applications for local pharmaceutical services (LPS) schemes in guidance issued by the Department of Health, according to the National Pharmaceutical Association...[more]

Research trust seeks £10m fund The Pharmacy Practice Research Trust has launched a campaign to raise £10m to fund its "Medicines and people" programme...[more]


RESEARCH AND DEVELOPMENT

Promising vector for HIV vaccine but virus could escape host response Researchers have shown that a vaccine against the simian immunodeficiency virus (SIV) induces cellular responses that can contain, but not prevent, infection. However, surviving viruses could mutate and avoid the host immune response, say the authors of a second study...[more]

HIV vaccine within reach but politics will decide An effective, affordable and accessible HIV vaccine is within reach but whether or not it is ever developed is dependent on politics. This is the view of researchers from the Medical Research Council of South Africa...[more]

New cancer vaccines aim to boost natural immunity Cancer vaccines that are in development are unlike traditional vaccines but all aim to boost immunity, according to a report published by the Association of the British Pharmaceutical Industry...[more]

Synthetic antioxidant prevents onset of type 1 diabetes in mice A synthetic antioxidant, AEOL 10113, can prevent the onset of type 1 diabetes, a new study suggests...[more]

Positive results for Huntingdon's Two phase II studies have shown thatLAX-101 might reduce the severity of Huntington's Disease...[more]

Breast cancer drugs show synergistic effect when given in combination Using trastuzumab (Herceptin) in combination with ZD1839 (an anilinoquinazoline currently in development) has a synergistic inhibitory effect on the growth of breast cancer cells, say researchers...[more]

Study suggests sirolimus does not share tumour promoting properties of other immunosuppressants The immunosuppressant drug sirolimus (Rapamune), also known as rapamycin, does not stimulate the cancer growth seen with older drugs such as ciclosporin, say German researchers...[more]

Structure and action of third toxic anthrax protein revealed in Nature The structure of the third anthrax toxin, oedema factor (EF), has been published in Nature...[more]

Cannabis-based medicines on trial Cannabis-based medicines are to be tested in clinical trials for their effect on cancer pain...[more]


NEWS IN BRIEF
 

CHI arms cancer patients A booklet containing questions that cancer patients can ask health care professionals has been launched by the Audit Commission and the Commission for Health Improvement. The booklet also contains a description of the standards of care that providers should be offering. The two commissions hope that the list of essential questions and the hallmarks for care will help patients to push for improvements to the services they receive.

New chairman for SIGN Professor Gordon Lowe, professor of vascular medicine at Glasgow Royal Infirmary, has been appointed chairman of the Scottish Intercollegiate Guidelines Network. His appointment follows the death of the previous chairman, Professor Jim Petrie, last year.

GSK could sell off R&D units GlaxoSmithKline may consider selling off its recently established centres of research excellence in the future if they do not come up with successful new drugs. Dr Tachi Yamada, GSK's head of research and development, said that he was not yet certain whether the R&D units would be more successful than small biotechnology companies or university departments. "This debate will play out over the next decade. It could go both ways," he said. GSK established six centres of research excellence last year (PJ, 3 March 2001, p276), two of which are in the United Kingdom.

New PhEur implemented The 4th edition of the European Pharmacopoeia has now superseded the 3rd edition. In addition, 107 new and revised monographs are to come into force on 1 July. For the future, the pharmacopoeia will be updated using non-cumulative supplements. Two, 4.1 and 4.2, have already been published and three further supplements will be published each year while the 4th edition is in force.

NPA website revamped The National Pharmaceutical Association has revamped its www.npa.co.uk website, which gives the association a public face on the internet. The revised website includes NPA policy statements. The members only section of the website is to be closed down shortly. Member access to the NPA on the web will be by registration with NPAnet.

Superdrug to run brown bag month Superdrug is to run a brown bag scheme through its 230 pharmacies this month encouraging customers to return out-of-date or unwanted medicines. Research carried out for Superdrug revealed that of 1,000 adults surveyed, 60 per cent had medicines which were a year or more old in their homes, with one in 12 having medicines over five years old. The most common were analgesics and antibiotics.

Moss osteoporosis counselling Moss Pharmacy is to offer counselling and monthly follow up telephone calls to patients taking Eli Lilly's product Evista (raloxifene). Twenty-five pharmacists will take part in the six-month programme. Each patient will have an initial counselling session with the pharmacist. They will then receive a monthly newsletter providing more information on their condition and its treatment and a telephone check up from the pharmacist. Compliance with the treatment will be analysed at the end of the programme.


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