Home > PJ (current issue) > Onlooker | Search

Return to PJ Online Home Page

The Pharmaceutical Journal
Vol 268 No 7184 p186
9 February 2002

This article
Reprint
Photocopy

   

PDF* 45K

Onlooker

Tipsy boatmen [more]
Hounds of Hell [more]
Sleep well [more]


Tipsy boatmen

Ever since humans started to make voyages across the oceans, sailors have had the reputation of a fondness for alcoholic. Perhaps this stemmed from an idea that, on the broad watery wastes, collisions were unlikely, so that a clear head was not a necessity, as it must be in transport over land. That there are snags in the notion has been suggested every now and then when a large transport vessel involved in an accident has revealed that crew members were incapacitated by liquor or its consequent somnolence.

That this situation applies also to inshore navigation appears from a paper published in the Journal of the American Medical Association for 19 December 2001. A study is reported of alcohol use and recreational boating fatalities in Maryland and North Carolina. The results indicate that drinking not only increases the risk of people falling into the water but also reduces the chance of survival from such an accident. A strong positive association was found between blood alcohol concentration and relative risk from drowning or death from hypothermia, not only to the drunken navigator but to passengers also, irrespective of whether the boat was moored or under way. There was an odds ratio of 1.3 at a concentration of 10mg/dl compared with 52 at one of 250mg/dl that a fatality would occur.

Alcohol impairs balance and co-ordination, so increasing the chance of falling overboard. Impaired judgement resulting from a high blood alcohol concentration also increases the risk that a hazardous situation will be encountered during a trip. Thus, it is not only the person in charge of the boat but everyone on board who is in peril. Moreover, once a person enters the water the ability to keep head above water is diminished by alcohol, and hypothermia or drowning becomes likely.

It is remarked that alcohol consumption has long been part of recreational boating, and drinking during such activity is reported by 30 to 40 per cent of boaters. Most fatalities involve drowning, and only 18 per cent can be attributed to the physical effects of colliding with other boats or floating objects.

Back to Top


Hounds of Hell

Black dogs in a plethora of situations feature prominently in folklore. Indeed, when Theo Brown, the Devonshire folklorist, set out some years ago to write a book on the subject of black dogs, she found herself overwhelmed by the mass of information available in the literature, and died before she could accomplish her ambition.

I am prompted by a fascinating article in The Countryman for February which describes strange happenings, not this time in Devonshire but on the borders or Norfolk and Suffolk. The records of the church of St Mary in Bungay claim that on Sunday 4 August 1577 a violent thunderstorm shook the church in question, accompanied by a fearful black dog which entered the nave unseen by the assembled parishioners. Two persons who were touched by the animal were promptly killed and a third shrivelled "like a drawn purse." Even stranger, on the very same day, seven miles away in the church at Blythburgh, three parishioners were killed and others "blasted" by a black dog which entered the building, an event duly recorded in the church documents.

It is claimed also that in the neighbourhood of Dunstable there was a local belief that ghostly black hounds of the size of retrievers haunted fields at night and were in the habit of killing anyone who dared to shout at them. Some of these were said to be headless.

The legends of black hounds in the West Country are less savage, but there are many of them, widely distributed. A general superstition relates that places where three tracks meet are guarded by black dogs.

Sir Robert Chichester of Martinhoe is said to traverse the parish in the form of a black dog sitting in a flaming car drawn by four elephants, which seems unnecessarily extravagant. A youngster living in a house between Postbridge and Widecombe that was claimed to be haunted, lamented that he was terrified by a pack of black hounds running loose in the courtyard, although no one else could perceive them. There are black dogs reported from Torrington, and haunting the road between Moretonhampstead and Postbridge. The celebrated hound of the Baskervilles, described by Arthur Conan Doyle, was based upon a similar report current in the neighbourhood of Princetown.

Perhaps the best-known black dog legend is attached to the notorious Lady Mary (or perhaps Frances) Howard of Tavistock (1596-1671),who lived at Fitzford. She was a lady-in-waiting to Henrietta Maria, had four husbands, and was reputedly vastly rich and vicious.

One version of the story maintains that Lady Howard was obliged to atone for her misdeeds by running nightly from Fitzford to Okehampton in the shape of a black hound, plucking each time a blade of grass from the castle mound and returning with it. She is accompanied by a headless coachman driving a coach made of bones. An alternative story relates that the lady drives the coach and is preceded by a black hound with a single eye in the middle of its forehead.

If you have ever had to walk that particular road after dark on a stormy winter's night, you will appreciate that the setting is highly appropriate and not to be faced by the timid traveller.

Back to Top


Sleep well

A recent report has indicated that although most disorders of sleep are associated with medical or psychiatric conditions, some are induced by commonly prescribed drugs. According to a report in The Lancet for 12 January, little research is being done on such side effects. Listed among compounds that have come under suspicion are methylxanthines, ethanol, non-sedating antidepressants and drugs intended to relieve parkinsonism.

One biologically active compound closely concerned with sleep induction is adenosine. Accumulation of extracellular adenosine in the brain apparently promotes the onset of sleepiness following a long period of wakefulness. Methylxanthine drugs probably disturb sleeping patterns through this pathway. Caffeine is a notorious example. There are many other neurotransmitters concerned with sleep, and interaction with any of these may disturb rest.

There are discrepancies between data obtained in sleep laboratories and subjective complaints from patients. Many recently developed antidepressants decrease the fraction of REM sleep but how this relates to subjective sleep disturbances is not known. Most serotonin reuptake inhibitors probably induce sleeplessness by stimulating 5-hydroxytryptamine postsynaptic receptors. Dopamine agonists are known to induce nightmares.

But until the molecular basis of sleep regulation has been thoroughly understood, the precise effects of drug treatment upon sleeping patterns will remain obscure.

Back to Top


Home | Journals | News | Notice-board | Search | Jobs  Classifieds | Site Map | Contact us

©The Pharmaceutical Journal