Home > PJ (current issue) > Onlooker | Search

Return to PJ Online Home Page

The Pharmaceutical Journal
Vol 268 No 7190 p410
23 March 2002

This article
Reprint
Photocopy

   

PDF* 50K

Onlooker

Taking a chance with fungi [more]
Aux armes, citoyens! [more]
Pill colour may determine outcome [more]


Taking a chance with fungi

When I worked in a small rural pharmacy in the lap of the South Downs and surrounded by much woodland and pasture administered by the National Trust, I was frequently asked to identify fungi that people had discovered in the wild and wished to eat provided they were identified as safe.

As it happens, I had some knowledge of these tricky plants, having attended several extramural classes on the practical aspects of the subject. Nevertheless, quite a few puzzling samples were submitted, and the rule where fungi are concerned is "when in doubt, don't". Accurate classification is the first essential.

I note that some correspondence published in New Scientist for 2 March is devoted to the question of gathering and consuming edible fungi. One writer points out that in continental Europe gathering wild "mushrooms" is a popular pastime, and goes with widespread knowledge of types, whereas in Britain few people can distinguish between them. The answer given is that the British probably never had any fungus lore, and so it is not so much a loss of knowledge as a lack over generations.

All over the world there are mycophobes and mycophiles. An expert from the Royal Botanic Gardens in Kew remarks that poisoning cases throughout some continental countries "make gruesome reading", and that the supermarket is the safest place to foray for funguses. However, truffles are identified in many countries by dogs and pigs. Other species are less certain.

On the shady side, there has now and then been a craze for collecting hallucinogenic fungi deliberately for drug misuse. If those who misuse "magic mushrooms" really appreciated how mistaken they may be in their identification, they might steer clear of so dangerous a practice. In any event, the popular idea that a fungus is edible if it peels readily and does not tarnish a silver spoon when cooked with it has long been discredited as asking for trouble.

Back to Top


Aux armes, citoyens!

The notion of citizenship comes to us from ancient Greece, where it was contained in two principles. First it denoted the limits of a state with its distinct boundaries. Secondly, it implied the participation of residents as joint proprietors. Those calling themselves citizens — originally those composing a city, but later by extension to occupants of a circumscribed state — shared in public responsibilities and in public privileges, in the same way as shareholders in a modern company partake of those obligations and privileges.

According to the Greek concept, which was adopted with modifications by Rome, citizenship conferred freedom of speech in state assemblies and a measure of equity between rulers and ruled. By a later development, it became possible to assume citizenship through purchasing power.

It is not possible to determine precisely what our government means when it talks of including citizenship as a compulsory element in the school curriculum. Recent criticisms have indicated that science will be included in citizenship teaching. For example, science teachers would be expected to hold discussions with their students on such troubling topics as genetically modified crops and animals, and nuclear power. In the past, it appears that most classroom discussions concerning biomedical issues have been included in humanities lessons, not science instruction.

An editorial in Nature for 7 March stresses that science seems to have been squeezed as an afterthought into "citizenship" without thought for additional resources of teaching time or money. And "it will strike many science teachers in England as ironic that, a decade or so into the restrictive autocracy of the national curriculum, they are now expected to be more flexible and free-thinking."

Nature makes the slightly sinister comment that the citizenship agenda may be intended to overcome the growing reluctance among young people to participate in politics, a tendency that the politicians like to call apathy. That youngsters should regard politics, and democratic voting, as a remote affair which has little effect on their daily lives, is not surprising, and stems from the behaviour of our political leaders, in government and in local administration. They are trying to impress upon schoolchildren that voting for a candidate and taking part in political processes is an essential part of human existence.

What our political leaders fail to appreciate is that, when faced with a voting paper offering a choice between a half-wit and a dishonest schemer, you are tempted to deface your paper. And, when trying to get right out of wrong through your representative, you are as likely as not to encounter meaningless equivocation and endless procrastination that will discourage you in future. Can you, by introducing citizenship (whatever is meant by the word), inspire more able future politicians to emerge from the classroom?

Back to Top


Pill colour may determine outcome

A commentary in the Journal of the American Medical Association for 6 February, from Harvard, describes side effects that occur in patients taking active medications as divisible into two types. What are called "specific side effects" are symptoms or physical changes that depend upon the biological and pharmacological activity of the drug in question, and are predictable and dose dependent. By contrast, "non-specific side effects'' cannot be explained by reference to the known pharmacology of the drug; they are idiosyncratic and bear no relation to the size of the dose taken. In this second instance, such unexpected effects may be positive and beneficial, or they may be negative and adverse for the patient. In clinical practice it is the adverse reactions that attract most attention.

It is significant that about a quarter of those patients who receive a placebo in a controlled trial report that they have experienced adverse side effects. If they are closely questioned by their medical practitioner when undergoing treatment, even more describe unwanted effects of their placebo drug. Symptoms reported include headache, drowsiness, fatigue and insomnia. They are frequently attributable to information gathered by a patient from the lay media or the manufacturer's advertising matter.

In addition, the colour or shape and sometimes the name of a prescribed tablet may inspire non-specific side effects. For example, red, orange or yellow tablets tend to be associated with stimulant effects, whereas blue or green signifies sedation.

Since non-specific side effects often distress anxious patients and lead to both wasted medication and non-adherence to dosage directions, prescribers would be wise to take into account the personal characteristics and social situation of the patient before the details of a possible treatment are settled.

Back to Top


Home | Journals | News | Notice-board | Search | Jobs  Classifieds | Site Map | Contact us

©The Pharmaceutical Journal