The Pharmaceutical Journal
Vol 268 No 7194 p521-527
20 April 2002

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Medicines Control Agency (www.mca.gov.uk)

Zyban safety update

Following guidance on the use of smoking cessation therapies by the National Institute for Clinical Excellence last week, the Medicines Control Agency has issued a safety update for bupropion (Zyban). The MCA says that up to 8 April 2002, a total of 7,472 suspected adverse reactions have been reported via the yellow card scheme in the UK.

Since the last safety update (PJ, 26 January, p86), one report of a suspected adverse reaction with a fatal outcome has been received bringing the total to 58.