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The Pharmaceutical Journal
Vol 268 No 7196 p597-604
4 May 2002


News summary

Control of entry will not apply to local pharmaceutical services contracts Local pharmaceutical services pilot schemes will not be governed by National Health Service rules covering the control of entry into contracts or the terms of service for pharmacy contractors...[more]

Transformation for Scottish NHS A central role for local primary care teams in transforming the National Health Service in Scotland was announced last week...[more]

Gear up for more POM-to-P switches Medicines will be available over the counter through pharmacies more quickly under a new reclassification process launched on 1 May...[more]

Importers can repack products Trade mark holders cannot legitimately object to products being repackaged by parallel importers if that makes it impossible for importers to market their goods, the European Court of Justice (ECJ) has ruled...[more]

Pharmacists best at treating head lice Ignorance among community health professionals of how to manage head lice is hampering control of the problem...[more]

Too few trainees in hospital pharmacy Vacancies for hospital pharmacists are falling, but there are more vacant posts than there are hospital pharmacists in training...[more]

NPA to challenge fatal accident inquiry finding A Scottish fatal accident inquiry finding that blames a pharmacist for a patient's death is to be challenged by judicial review...[more]

Interferon beta-1b every other day more effective than weekly interferon beta-1a Interferon beta-1b administered every other day is more effective than weekly interferon beta-1a for multiple sclerosis (MS), researchers say...[more]

Serono still claims benefits for Rebif over Avonex Further data from a head-to-head study comparing two brands of interferon beta-1a in multiple sclerosis indicate that patients treated with Rebif, manufactured by Serono (the company that conducted the study), are more likely to remain relapse free than patients treated with Avonex...[more]

Mycophenolate halts renal decline in transplant patients Substituting mycophenolate mofetil (CellCept) for ciclosporin in kidney transplant patients can halt deteriorating kidney function, a new study shows...[more]

Current Problems in Pharmacovigilance The latest edition of Current Problems in Pharmacovigilance (2002;28:1-6) has been published by the Medicines Control Agency and Committee on Safety of Medicines...[more]

Pet owners should be aware of range of outlets for veterinary medicines Veterinary surgeons should make customers aware that they can obtain medicines on prescription from other sources such as pharmacies, according to the Competition Commission, which is conducting an investigation into the supply of prescription only veterinary medicines...[more]

Molecular evidence discovered for trastuzumab’s cardiotoxicity Research published in Nature Medicine this week reveals direct molecular evidence that trastuzumab (Herceptin) causes cardiomyopathy...[more]

New combination psoriasis treatment A combination preparation containing calcipotriol and betamethasone dipropionate, Dovobet ointment, has been launched this week by Leo Pharmaceuticals for the treatment of psoriasis...[more]

H pylori breath test effective A breath test for Helicobacter pylori infection is as effective as endoscopy and causes less distress for patients, a study shows...[more]

Alosetron could be reintroduced A United States Food and Drug Administration advisory panel has recommended that GlaxoSmithKline be allowed to reintroduce alosetron (Lotronex), for irritable bowel syndrome, providing there are restrictions on who can prescribe it, and patients are followed up...[more]

Gene study seeks 500,000 volunteers Funding of £45m has been announced for a study into the role of genes and the environment in health and disease...[more]

Interruptions to HIV treatment might enhance viral replication A study published in Nature has placed a question mark over the practice of structured treatment interruptions, or drug holidays, in patients infected with HIV...[more]

WHO takes steps to make HIV treatment more accessible The World Health Organization has issued guidelines for the treatment of HIV/AIDS in poor countries...[more]

Hand gels fail microbial efficacy test Researchers who tested 10 alcohol-based hand gels found none met the European standard by which microbial efficacy is measured...[more]

Nucare launches website ...[more]

Numark signs 1,500th shareholder ...[more]

Free stock for Vantage loyalty ...[more]

Fatal injection doctors arrested ...[more]


Research and Development

Oral ganciclovir prodrug effective in treatment of cytomegalovirus retinitis An oral prodrug of ganciclovir, valganciclovir (Valcyte), appears to be as effective as intravenous ganciclovir for initial treatment of cytomegalovirus retinitis in patients with AIDS, a new study shows...[more]

New immunosuppressant reduces rejection in transplant patients A new immunosuppressant, everolimus (Certican), has been shown to reduce acute rejection and graft vasculopathy following heart transplantation...[more]

Oral cytokine inhibitor effective as anti-inflammatory agent in rheumatoid arthritis An oral cytokine inhibitor, pralnacasan, has been shown to have anti-inflammatory effects in rheumatoid arthritis...[more]

New asthma treatment promising A leukocyte suppressing anti-inflammatory drug (LSAID) for the treatment of asthma has shown promising results in a phase II trial...[more]

S-Enantiomer of citalopram effective for depression Escitalopram, the S-enantiomer of citalopram, is effective and well tolerated for the treatment of depression, a new study shows...[more]

Plasma protein inhibitor raises HDL Use of a cholesteryl ester transfer protein inhibitor, JTT-705, in humans is an effective way to raise high-density lipoprotein (HDL) levels, a new study shows...[more]

Ethical safeguards needed for research in developing countries Medical research in developing countries funded by organisations in wealthy countries must be subject to rigorous ethical safeguards, according to a report published by the Nuffield Council on Bioethics...[more]

Vitamin C transporter deficiency leads to death in newborn mice Mice lacking the vitamin C transporter SVCT2 die within minutes of birth, American researchers have found. This may have important implications for human health, they say...[more]

Peptide protects against malaria A peptide, derG, has been found to provide 100 per cent protection against malaria infection in a mouse model...[more]

New oxazolidinone shows potential AstraZeneca's new antimicrobial oxazolidinone, AZD2563, shows potential for use in combination with other antibiotics, new data shows...[more]

Factor Xa inhibitor well tolerated DX-9065a, an anticoagulant that selectively and reversibly inhibits factor Xa, is well tolerated in patients with stable coronary artery disease, researchers report...[more]


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