The Pharmaceutical Journal
Vol 269 No 7214 p319-323
7 September 2002

This page
Reprint
Photocopy

PDF* 65K

  Emergency hormonal contraception (EHC)
  Olanzapine
  Drug interactions
  Consent
  Tablet crushing
  Modernisation
  The Society

Letters to the Editor

Drug interactions

Sumatriptan and fexofenadine

From Mr A. P. Bolt, MRPharmS

I would like to report a possible drug interaction that happened to me. For many years I have been taking sumatriptan for migraine treatment without significant adverse effects.

I was prescribed fexofenadine for hay fever. After a few days of taking fexofenadine I had a migraine attack. About 10 minutes after I took 100mg sumatriptan I got a crushing chest pain which resolved in about 15 seconds. This is a well reported adverse effect of sumatriptan which I had not experienced before or since I stopped the fexofenadine. I do not wish to repeat the experience to "prove" the link.

Alistair Bolt
Medicines Information Pharmacist
Norfolk & Norwich University Hospital, Norwich

Send your letter to The Editor

Previous Topic (Olanzapine)
Next Topic (Consent)