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The Pharmaceutical Journal
Vol 269 No 7217 p436
28 September 2002

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Products

    Prescription Products SPC changes Discontinued products Supply problems Counter medicines

Alert Cytarabine injection


Prescription Products

FemSeven Sequi

Packs of FemSeven Sequi transdermal patches containing patches of estradiol hemihydrate 1.5mg per patch (releasing 50µg of estradiol per 24 hours) and patches of estradiol hemihydrate 1.5mg and levonorgestrel 1.5mg per patch (releasing 50µg of estradiol and 10µg of levonorgestrel per 24 hours) have been launched (Merck Pharmaceuticals); net price, 4 £9.98, 12 £28.44. The product is indicated for hormone replacement therapy for oestrogen deficiency symptoms in post-menopausal women who still have their uterus. Each treatment cycle consists of applying one estradiol patch once a week for the first two weeks and then one estradiol and levonorgestrel patch once a week for the following two weeks.

Aranesp injection

A 300µg/0.6ml prefilled syringe of Aranesp (darbepoetin alfa) solution for injection has been launched (Amgen); net price, 1 £502.80.

PLIVA products

PLIVA Pharma (formerly Dominion Pharma) has launched the following products:

• Doxazosin tablets; net price 1mg 28 £9.50, 2mg 28 £12.68, 4mg 28 £14.68

• Ceftriaxone sodium 1g powder for injection; net price, 1 £10.94

Goldshield products

Goldshield Pharmaceuticals has launched the following products:

• Soloc (bisoprol fumarate) tablets; net price, 5mg 28 £8.15, 10mg 28 £9.15

• Trintek 5 (glyceryl trinitrate) transdermal patches (releasing 5mg/24 hours); net price, 30 £11.84

• Trintek 10 transdermal patches (releasing 10mg/24 hours); net price, 30 £13.10

• Trintek 15 transdermal patches (releasing 15mg/24 hours); net price, 30 £14.42

Reminyl oral solution

Reminyl (galantamine) 4mg/ml oral solution, pack size 100ml, has been launched (Shire Pharmaceuticals); net price, £120.

Erythromycin oral solution

Erythromycin oral solution 250mg/5ml and 500mg/5ml, pack size 100, are now available with a child resistant cap (Alpharma).

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SPC changes

Aranesp new indication

The licensed indications for Aranesp (darbepoetin alfa) solution for injection have been extended. Aranesp is now also indicated for the treatment of anaemia in adult cancer patients with solid tumours (non-haematological malignancies) receiving chemotherapy).

Diovan capsules

The summary of product characteristics for Diovan (valsartan) capsules has been updated (Novartis Pharmaceuticals). The following undes-irable effects, which have been reported very rarely since the product was licensed, have been added: thrombocytopenia, myalgia and transient taste disturbance. See SPC.

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Discontinued products

AstraZeneca products

The following products will be discontinued with effect from 31 October (AstraZeneca):

• Dirythmin SA (disopyramide) 150mg Durules

• Theo-Dur (theophylline) 200mg and 300mg tablets

Further information can be obtained from the company'es medical information department (tel 0800 783 0033).

Acticin gel and cream

Acticin (tretinoin) 0.025 per cent gel and cream will be discontinued as of 31 October (Strakan).

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Supply problems

Guarem granules

Packs of 50 sachets of Guarem (guar gum) 5g granules are out stock (Shire Pharmaceuticals). No further stock of this pack size is expected. The 100-sachet pack size remains available. Further information can be obtained from the company's medical information department (tel 01256 894000).

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Counter medicines

Remegel chewy squares

Remegel (calcium carbonate) chewy indigestion squares have been launched in a summer fruit flavour (SSL International); retail price, 8 95p, 24 £2.35. Legal category: general sale list.

Rennie Soft Chews

Rennie Soft Chews (calcium carbonate) have been launched (Roche Consumer Health); retail price, 8 £1.15, 3 x 8 £2.69. The product is available in a mint flavour. Legal category: general sale list.

Lyclear cream rinse

The packaging for Lyclear (permethrin) cream rinse has been redesigned as shown below (Pfizer Consumer Healthcare).

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