The Pharmaceutical Journal
Vol 269 No 7222 p633
2 November 2002

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Gabapentin and neuropathic pain

Gabapentin reduces pain and improves some quality-of-life measures in patients with neuropathic pain, say British and Irish researchers (Pain 2002;99:557). A randomised, controlled trial involving 305 adults showed that the average daily pain score decreased more for patients treated with gabapentin than for patients given placebo (7.3 to 6.3 versus 7.1 to 5.6, P=0.048). After eight weeks of treatment gabapentin resulted in a 50 per cent or greater reduction in mean pain score in 21 per cent of patients compared with 14 per cent of patients given placebo (P=0.16). The study was funded by Parke-Davis.