The Pharmaceutical Journal
Vol 269 No 7225 p735
23 November 2002

This article
Reprint
Photocopy

News summary

Low-dose doxycycline for the heart

A sub-antimicrobial dose of doxycycline could be used to modulate inflammation in acute coronary syndromes.

Researchers randomised 50 patients to receive doxycycline 20mg or placebo twice daily for six months and found that levels of C-reactive protein and interleukin-6 (markers of inflammation) were reduced by 46 per cent and 34 per cent, respectively, in the doxycycline group.