The Pharmaceutical Journal
Vol 270 No 7237 p259
22 February 2003

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Vit B1 prevents diabetes progression

A derivative of vitamin B1 prevents the progression of diabetic complications such as retinal damage, researchers report. They fed diabetic rats benfotiamine, a fat-soluble synthetic analogue of vitamin B1, for nine months and found that the compound interferred with three major pathways of high-glucose damage and prevented diabetic retinopathy.

The research is due to be published in the March issue of Nature Medicine but is available now via the Nature website.