The Pharmaceutical Journal
Vol 270 No 7247 p605
3 May 2003

This article
Reprint
Photocopy

News summary

Related websites
BMJ abstract (more)

Therapy for overactive bladder

Anticholinergics can improve overactive bladder symptoms but the benefits are of limited clinical significance, researchers report.

They reviewed 32 randomised trials comparing anticholinergic drugs (tolterodine, oxybutynin, trospium, propiverine, emepronium and propantheline) with placebo. Active treatment resulted in small improvements in symptoms and a reduction in the number of leakage episodes a day compared with placebo (BMJ 2003;326:841).