The Pharmaceutical Journal
Vol 270 No 7250 p713
24 May 2003

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The Lancet (www.thelancet.com)

Anticonvulsant role in nausea

Gabapentin (Neurontin) might have a role in treating chemotherapy-induced nausea, a small open-label study shows.

Breast cancer patients were given gabapentin 300mg three times a day for two out of four rounds of chemotherapy. Gabapentin was associated with reductions in both acute and delayed chemotherapy-induced nausea, and three out of nine patients had complete resolution of nausea when taking gabapentin (Lancet 2003;361:1703).