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The Pharmaceutical Journal
Vol 271 No 7267 p357
20 September 2003

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Technology appraisal programme of the National Institute for Clinical Excellence: a review by WHO (PDF 900K)
Health Select Committee report on the National Institute of Clinical Excellence (PDF 610K)


WHO commends NICE processes

The National Institute for Clinical Excellence has been praised by the World Health Organization for achieving an international reputation in only four years. But the praise is tempered by concern that pharmaceutical companies are too close to the appraisal process and by conflicts between transparency and confidentiality.

A WHO review team said that published NICE appraisals are already being used as international benchmarks and that this was clear recognition of their credibility. However, the team said that although the transparency of the appraisal process and intensive participation of stakeholders was a significant achievement, it was necessary to reconcile the inherent contradiction of transparency and the institutes acceptance of confidential material from drug companies. There was also concern about the inclusion of company employees on appraisal committees.

“Although there is a need to ensure that manufacturers’ views are taken into consideration, this should not be through membership of the appraisal committee but through the consultation process,” a WHO report says (PDF 900K).

WHO was asked by NICE to review its processes following a House of Commons Health Select Committee recommendation last year that an independent review of a selection of NICE appraisals should be carried out.


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