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The Pharmaceutical Journal
Vol 271 No 7269 p447
4 October 2003

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Letters to the Editor

Medical research

Creating worry rather than informing patients

From Mr I. L. Marsha, MRPharmS

Health care professionals are often asked by patients, or members of the public in general, to interpret news of medical research — commonly new treatments or fresh findings on known diseases — that they have heard about through television, the radio, newspapers, the internet, or friends and family.

Research is often a highly competitive focus on a particular type of patient; this may well lead to difficulties for health care professionals in explaining seemingly antagonistic news releases to an increasingly confused lay community.

It is right that the results of research on health matters are disseminated as soon as possible, but announcements should be made in a measured and sensitive way, so as not to cause undue concern. However, time and time again this fails to happen in medicine as well as in politics.

Taking one particular example, various articles in the press recently — both tabloid and broadsheet — reported on research into associations between diet and breast cancer. These were based on a survey designed by Cancer Research UK. The press release for this was entitled, “Women loath to give up the good life to reduce breast cancer risk”. It discussed the attitude of women towards issues of alcohol, obesity and hormone replacement therapy when considering the risk of developing the disease. The Daily Telegraph stated, in a short article on the release: “Studies have shown that women who drank a glass of wine each day were six per cent more likely than non-drinkers to develop breast cancer by the age of 80”. Apart from asking how much significance this has to women in general, we are reminded of seemingly contradictory findings.

As reported in The Pharmaceutical Journal of 7 September 2002 (p310), researchers at Barcelona’s Cardiovascular Research Centre concluded in their study that “a moderate consumption of red wine induces an inhibitory effect on thrombosis, triggered by damaged vessel walls. Therefore, consumption of two glasses a day of red wine could be considered as a protective factor for cardiovascular risk.” This benefit of alcohol had again been widely reported in the press.

Did the newspaper item cited above on the Cancer Research UK’s press release represent proportionate reporting? The level of exposure of the mammary tissue to oestrogen throughout a woman’s lifetime is a factor in breast cancer development; women are therefore entitled to feel, for example, that if they are being treated with HRT they should take advice and, depending on personal circumstances, review this treatment. A combination of moderate exercise with a balanced diet is an aspect of lifestyle which may in general reduce the risk of developing breast cancer, by helping to moderate the body’s quantity of oestrogen-producing adipose tissue. What of the consumption of regular but small amounts of alcohol, though?

If indeed harmful in this scenario, it may be pertinent to ask if women working in aseptic production units, being continuously exposed to industrial methylated spirit and the like, are at significant risk.

The deliberations of the Hutton Inquiry provide a salutary lesson for everyone involved in the reporting of medical issues. “Single source intelligence”, properly verified, has its place; however, experience has shown that when this is given undue prominence, it may be open to misinterpretation. The results of research reported in the press are frequently handled indelicately. In the search for sound bites, material may be accused of being “sexed up”, not informing but merely creating worry among the general population.

Ian Marsha
Aseptic Services Pharmacist and Teacher-Practitioner
Department of Pharmacy and Pharmacology,
University of Bath

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