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The Pharmaceutical Journal
Vol 271 No 7276 p709
22 November 2003

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Letters to the Editor

EpiPens

Problems with expiry dates

From Mr D. Reading

The Anaphylaxis Campaign is a national charity that supports people with life-threatening allergies. It has come to our notice that there are occasional problems relating to the dispensing of the EpiPen auto-injector — a device prescribed to people at risk of anaphylaxis.

We have discovered that some EpiPens are being distributed with an unacceptably short period from collection at the pharmacy to the expiry date. ALK-Abello, the company that distributes the EpiPen in the United Kingdom, affirms that no EpiPen will leave its office with a shelf-life of less than nine months.

We asked our members, via our June newsletter, to let us know if they had been prescribed an EpiPen with an unacceptably short “shelf life”. A total of 36 members responded out of a membership of 7,400.

In the worst case, the mother of a severely allergic child collected two EpiPens in January 2003 and was alarmed to see they both expired the following month. Another person was prescribed two EpiPens in March 2003. One had two months before expiry and the other had three months. Four people were prescribed EpiPens with three months between collection and expiry, five people reported a four-month period and five people a five-month period.The rest reported expiry periods of between six and eleven months.

It is possible that the problem occurs because EpiPens remain on the pharmacy shelf until requested, and by then they may have a very short shelf-life. This situation presents an understandable difficulty for the pharmacist, who will find it impossible to judge when an EpiPen will be requested. To order stock only when in receipt of a prescription could endanger a patient, who would be left without their emergency treatment.

The professional standards directorate of the Royal Pharmaceutical Society has advised that we inform our members to tell their local pharmacist well in advance when their current EpiPen is nearing its expiry date. This will allow the pharmacist to order the stock required in advance. We will certainly convey this message to our members, but would point out that our membership represents only a small proportion of EpiPen carriers.

We would respectfully ask pharmacists to play their part and seek to ensure that they are not providing patients with EpiPens that are approaching their expiry dates.

David Reading
Director, Anaphylaxis Campaign

www.anaphylaxis.org.uk

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