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The Pharmaceutical Journal
Vol 271 No 7278 p767
6 December 2003

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Health Protection Agency: Malaria guidelines (more)


Pharmacists advised to read updated malaria prevention recommendations

Pharmacists are being urged to read new malaria prevention guidelines published by the Health Protection Agency.

The updated guidelines, which contain specific recommendations for individual countries, now have greater emphasis on mefloquine, doxycycline and atovaquone/ proguanil as the three options for highly chloroquine-resistant falciparum malarious areas.

Dr Barbara Bannister, clinical head of service, infection and immunity at the Royal Free Hospital, London, and one of the guideline authors told The Journal that travellers may not realise their knowledge could be out of date. “People may remember times when relatively simple measures were effective, such as taking chloroquine once a week, but the susceptibility of malaria to these regimens has diminished.” She added: “If a patient goes into a pharmacy to buy chloroquine the pharmacist is in an excellent position to check that chloroquine is the correct drug for their destination.”

Writing in an editorial to accompany the guidelines, which are due to be published in the journal Communicable Disease and Public Health (2003;6:180), Dr Bannister says that widespread self-medication, which may include suboptimal dosage and inadequate duration of treatment, leads to the rapid emergence of drug resistance. She says that longer-term antimalarial treatment is safe as long as contraindications such as pregnancy are observed.

“Continuing prophylaxis can be confidently advised for those intending to live or work long term in malaria endemic countries,” she writes.

Pharmacists are advised to read in particular the section of the guideline that covers the health care workers’ consultation with prospective travellers. This section includes information about the risks of getting malaria and about malaria prevention.

Dr Bannister pointed out that people returning to malarious regions are highly represented among cases of malaria diagnosed in the United Kingdom. “People who originate from that area may feel they are resistant to malaria, or may remember the country from a time when malaria was well controlled.”

The guidelines also note that pharmacists are entitled to make yellow card reports to the Medicines and Healthcare products Regulatory Agency of adverse events believed to be related to use of antimalarials. Dr Bannister commented: “It is important for pharmacists to know that catching malaria when on prophylactic treatment counts as an adverse event.”

The guidelines can be accessed here.

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