The Pharmaceutical Journal
Vol 271 No 7279 p807
13 December 2003

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Related websites
Journal of Urology (www.jurology.com)

New prostate agents

A potential new agent for benign prostatic hyperplasia has been developed by a team at University College London.

Currently available treatments either inhibit the proliferation of prostatic cells or reduce the increased tone. The team identified an enzyme, Rho-kinase, in prostatic smooth muscle cells of rats and humans. An inhibitor demonstrated both smooth muscle relaxation and inhibition of smooth muscle cell proliferation in vitro (Journal of Urology 2003;170:2517).