The Pharmaceutical Journal
Vol 272 No 7282 p49
17 January 2004

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Molecular Cancer Therapeutics abstract (more)

Garlic product halts tumour

Producing allicin (diallyl thiosulfinate), an active component of freshly crushed garlic, in situ can halt tumour growth, researchers from Israel have shown. They bound the enzyme alliinase from garlic to a monoclonal antibody against a specific tumour marker, ErbB2. In the presence of amino acid alliin, tumour-localised alliinase produced allicin, which effectively killed ErbB2-expressing cells in vitro (Molecular Cancer Therapeutics 2003;2:1295).