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PJ Online homeThe Pharmaceutical Journal
Vol 272 No 7283 p76
24 January 2004

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British Journal of Cancer abstract (more)


Risks of complementary medicines need identifing

Pharmacists should work closely with other health care professionals to encourage patients, particularly those suffering from cancer, to discuss the benefits and possible risks of taking complementary or alternative medicines (CAMs) in conjunction with conventional therapies, according to Cordula Seydel, former medicines information manager at the Royal Marsden Hospital, London, and co-author of a recent study.

The researchers say doctors need to be able to identify the potential risks of CAMs. Use of CAMs is particularly common in patients suffering from chronic disorders such as cancers, they say, and these patients are likely to use conventional medicines regularly and simultaneously with CAMs, which may lead to potentially dangerous interactions.

The researchers used a multiple-choice questionnaire to estimate herbal medicine use among 318 patients who attended the outpatient departments at a specialist cancer centre. Of these patients, 51.6 per cent reported taking CAMs, including echinacea, evening primrose oil and St John’s wort. Of those using CAMs, almost one third were unsure of the purpose of the remedy they were taking, and 11 per cent of patients reported exceeding the recommended dose of supplements.

The authors found that most patients surveyed had discussed CAMs with their doctor. However, they suggest that medical practitioners may not have the knowledge or the time to do so routinely in outpatient clinics. Equally, patients may not accept the doctor’s opinion about potential interactions, and may argue that conventional cancer treatments are equally toxic.

Mrs Seydel pointed out that local and specialist medicines information centres can provide good sources of information on commonly used CAMs. “However, due to the lack of safety and efficacy information on many CAMs, it is often necessary to discourage their use in a sensitive manner,” she added.

The authors note that pharmacists have a key role in updating doctors and sharing important information gathered from patients and other health care professionals (British Journal of Cancer 2004;90:408).

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