Northern Ireland integrated medicines management
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Participants at this conference heard about the
integrated medicines management project in Northern Ireland. Christine
Clark reports
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This conference was organised by the Pharmacy Department
at United Hospitals Trust, Antrim, and was held at the Hilton hotel,
Templepatrick, Northern Ireland, on 5 March
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Length of stay and readmissions down in NI medicines management project
Reductions
in the length of stay and readmission rates are two key results of the
Northern Ireland integrated medicines management (IMM)
project,
according to researchers at United Hospitals Trust, Antrim, and Queens
University, Belfast. Other benefits include increased appropriateness
of medicines use, improved use of time for nurses and doctors and elimination
of waste. The project has been so successful that additional funding
has now been allocated to roll the project out to all wards at the United
hospitals group and to start a similar project at Craigavon Hospital.
The Northern Ireland IMM project is the first randomised, controlled
study in the UK to assess the impact of a multidisciplinary, cross-sector
process designed to improve the effectiveness of medicines usage.
Part of the impetus for the project was the realisation that morbidity
due to the unwanted effects of medicines created an additional raft of
work for the health service, said Norman Morrow, chief pharmacist, Department
of Health, Social Services and Public Safety, Northern Ireland. He estimated
that the combined costs of adverse reactions to medicines (at least 50
per cent of which were preventable) and adverse events involving medicines
amounted to 1 per cent of the overall NHS expenditure in Northern Ireland.
Therefore, he argued, although 12 per cent of NHS expenditure was for
medicines, this was, itself, giving rise to additional costs. He explained
how the IMM project was part of a strategic initiative to bring clinical
pharmacy skills to bear at every stage of the patient-care journey and
thereby to make the use of medicines safer and more effective. The project
was conceived as a multidisciplinary team effort from the beginning.
It was to empower people to use their skills to do things they had not
done before and also to release others to take on different tasks.
In Northern Ireland the DHSSPS allocates executive programme funds for
suitable innovation and modernisation projects and the IMM project was
funded through this route. This meant that additional staff could be
appointed for the project. In the event, the project was based at United
Hospitals in Antrim, where there was a well-established clinical pharmacy
service, and a team of five pharmacists and five technicians was appointed.

Anita Hogg: written information provided |
The admission medication history is often critical to a patient’s
future progress, explained Anita Hogg, pharmacist project co-ordinator.
Omissions or inaccuracies can be perpetuated during the hospital stay
and for a long time after if they are not identified and corrected. For
this reason the IMM process uses several sources, including GP and community
pharmacy records, to compile a complete medication history.
Inpatient monitoring is a proactive process that includes checking that
treatment outcomes are appropriate and acceptable and that medicines
are tolerated. “We pay special attention to medication changes
and take time to explain to the patients what the changes are and why
they have been made,” said Mrs Hogg. We also provide as much written
information as possible, she added. At the time of discharge, the pharmacist
prepares and signs off the discharge prescription. The discharge documentation
also includes a list of medication changes, up-to-date relevant laboratory
test results and education points that need to be reinforced for the
patient. This information is faxed to the GP and community pharmacist
on the day of discharge. In addition, patients are educated about their
treatments and medication record sheets are provided for reference.
Integrated medicines management project
The Northern Ireland integrated medicines management
(IMM) project involved a randomised controlled comparison of
integrated medicines
management and “usual pharmaceutical care”. The IMM
process involves the compilation of an accurate and complete drug
history on admission to hospital, intensive monitoring and patient
education during the inpatient stay, preparation of discharge medicines
and transmission of a written summary of medication changes and
intended outcomes to both GP and community pharmacist. Discharge
medicines are issued in 28-day packs instead of the usual three-day
supply. In addition, there is standardisation of the most commonly
used medicines across the primary and secondary sectors, in order
to minimise confusion for patients. Medical patients were eligible
for inclusion in the study if they satisfied one of five criteria:
· Prescribed four or more regular medicines
· Prescribed a high-risk medicine, eg, warfarin, digoxin
· Prescribed intravenous antibiotics on admission to hospital
· Taking antidepressants and aged 65 years or more
· Previous hospital admission within the past six months
The criteria for surgical patients were:
· Prescribed one or more regular medicines
· Prescribed a high-risk medicine, eg, warfarin, digoxin
· Prescribed intravenous antibiotics on admission to hospital
· Previous hospital admission within the past six months
The key outcome measures were length of stay,
medication appropriateness index (MAI) and number of readmissions
in the 12 months following
discharge. In addition, process measures included the frequency
of discrepancies between the accurate drug history and the Kardex,
the cost of patients’ own drugs discarded, nursing time devoted
to medicines rounds and turnaround time for discharge prescriptions.
The project started in 2001 and more than 900 patients have been
recruited. Preliminary results show that the length of stay has
decreased by about four days in the IMM group compared with the
control group. The readmission rate at three months has been reduced
by 11 per cent and at 12 months by 33 per cent. The IMM groups
also had significantly higher MAI scores than the control group. |
IMM project helps patients and carers and benefits the whole health
care team from both sectors
“Dispensary work is a waste of what I have learnt — robots
can dispense,” said
Alison Woods, technician project co-ordinator. Typically, Miss Woods
spends all her time on wards where she is responsible for the management
of the ward stocks of medicines. Each day she reviews the medicines Kardexes
to check what is required and deals with discrepancies, alerting the
pharmacist if necessary. One important task is servicing the medicines
trolley in time for the 10am medicines round — after a busy weekend
this can be cluttered with unnecessary items, expired products and even
items that should have been refrigerated. She ensures that the products
that are required are ready and available and removes products that are
no longer required. She checks patients’ own drugs and identifies
those that are suitable for reuse and also processes discharge prescriptions.
In addition, Miss Woods educates patients about inhaler use, when required. Carer’s perspective
“The medicines record [document] has given me a better understanding
of mum’s medicines and the side effects and what to watch for,” said
Heather Laverty, describing her mother’s experience of the active
arm of the IMM project. Mrs Laverty’s mother is 82 years old and
has numerous medical problems. Daily contact with the pharmacist during
the inpatient stay and help with sorting out two carrier bags full of
hoarded medicines had been valuable, said Mrs Laverty, but the medicines
record had become her “bible”. “This has given me the
information to keep mum in better shape,” she said. For example,
when her mother recently became constipated she discovered that the cause
was “helping herself to Imodium,” said Mrs Laverty.
Nurse’s perspective
Linda Ferris described how she felt threatened at first when, in 2002,
she took up her appointment at Whiteabbey Hospital [part of United
Hospitals Trust] and found a pharmacist “doing her job”.
On her 24-bed medical ward there are an average of 80 admissions each
month. Most patients are frail, elderly and receiving five or six medicines.
The 10am medicines round can take two nurses up to two hours to complete. “There
are numerous interruptions,” said Sister Ferris. “One benefit
of the IMM project is that we can get accurate drug histories, including
allergies and blood levels where appropriate, with a single phone call
to our pharmacist or technician.” Other major benefits are the
maintenance of the medicines trolley, “dedicated staff who know
our ward” and the readily available
information resource. The possible drawbacks are complacency and deskilling
among nurses, said Sister Ferris.
SHO’s perspective
“We spend more time with patients and less time writing Kardexes,
discharge letters and answering queries from the pharmacy,” said
Nicola Brown, senior house officer, Whiteabbey Hospital, describing the
impact of the
project on her practice. The IMM process often reminds us that we need
to monitor, stop or change medicines, she added. Another advantage is
that GPs receive legible discharge information. “Patients get the
medicines they need and we don’t get called by the pharmacy or
the GP to query the discharge prescription,” she said.
GP’s perspective
John O’Kane, a GP at The Oaks Practice, Cookstown, said that GPs
particularly welcome the use of 28-day packs and the legible documentation.
They are also pleased to have the opportunity to contribute to a joint
formulary and product standardisation initiatives. “We cannot see
any disadvantages and we would like to give total support,” he
said.

Alwyn Beresford: a large step forward |
Community pharmacist’s perspective
The IMM process is “a very large step forward in achieving the
level of communication that we need,” said Alwyn Beresford, community
pharmacist, Greenisland Pharmacy. The discharge information provided
by the IMM process is particularly helpful because it enables him to
ensure continuity of supply. He predicted that community pharmacists
would soon be providing similar services and believes that they would
dovetail well with this service. He suggested that pharmacists in the
two sectors should be able to alert each other to the more vulnerable
patients.
Case study
Mrs Fortunate A 72-year-old woman was admitted with a presumed
diagnosis of pneumonia and a painful swollen leg. Previous medical
history includes chronic obstructive pulmonary disease (COPD),
hypertension and ulcerative colitis. Five drugs were listed in
her medication history.
· When the pharmacist compiled a medication history it emerged
that she was taking 12 regular medicines. The seven that had been
missed included aspirin, an antihypertensive agent, a non-steroidal
anti-inflammatory drug and a calcium supplement.
· One of the medicines for ulcerative colitis was recorded at half
strength. One medicine was recorded as daily instead of twice a
day.
· The prescriptions were not synchronised so they would run out
at different times (pharmacist to sort out).
· Mrs Fortunate also had a large bag of patients’ own drugs
(technician to sort out).
Progress A chest infection was diagnosed and antibiotics prescribed
(advice offered about choice). A deep vein thrombosis was diagnosed.
· It turned out that five of her medicines had been started in
the past month for the swollen leg, including a circulatory agent,
an NSAID and three painkillers. These were all discontinued.
· Warfarin was prescribed (aspirin was discontinued later).
· The patient was educated about warfarin and about the use of
an inhaler that she had been prescribed for her COPD
Discharge A discharge prescription was prepared and signed off.
· Nine points were highlighted for the GP and community pharmacist.
· Synchronisation of medicines was requested.
In total, 21 interventions were made for Mrs Fortunate. |
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