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PJ Online homeThe Pharmaceutical Journal
Vol 272 No 7290 p309
13 March 2004

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MHRA proposal (PDF 170K)


Emergency exemption for chemical warfare antidote injections

Antidotes to chemical warfare agents are likely to be added to the list of medicines that can be injected by anybody to save life in an emergency. As a general rule, it is an offence to inject a medicine other than in accordance with the directions of an appropriate practitioner.

The Medicines and Healthcare products Regulatory Agency has started consultation on a proposal to add pralidoxime chloride and obidoxime chloride to the life-saving exemption list under the Medicines Act 1968. Both are used in combination with atropine sulphate to counter poisoning by nerve agents and organophosphate pesticides.

There is also a proposal to add smallpox vaccine to the list, subject to two restrictions: it must have been supplied by or on behalf of the Secretary of State, the devolved administrations or an NHS body; and the administration must be in response to officially suspected or confirmed spread of smallpox virus. In practice, administration is expected to be restricted to health care professionals.

Products already covered by the exemption are adrenaline 1mg in 1ml injection, atropine sulphate injection, chlorpheniramine injection, cobalt edetate injection, dextrose injection strong BPC, diphenhydramine injection, glucagon injection, hydrocortisone injection, mepyramine injection, promethazine hydrochloride injection, snake venom antiserum, sodium nitrite injection, sodium thiosulphate injection and sterile pralidoxime.


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