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PJ Online homeThe Pharmaceutical Journal
Vol 272 No 7296 p497
24 April 2004

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European Atherosclerosis Society (www.eas-society.org)


Rosuvastatin better than atorvastatin for reaching LDL targets

Treatment with the lowest dose of rosuvastatin (Crestor) enables more patients with type 2 diabetes to reach target low-density lipoprotein cholesterol levels than atorvastatin, according to the first comparative data in this group of patients.

Results showed that 94 per cent of patients with type 2 diabetes and dyslipidaemia treated with rosuvastatin (10mg daily) reached the new European LDL-cholesterol goal of <2.5mmol/L after eight weeks’ treatment. This compared with 79 per cent of those randomised to the same dose of atorvastatin (P<0.001). Results from the UK study, which included 509 patients, were reported earlier this week at the European Atherosclerosis Society congress held in Seville. The study was funded by AstraZeneca.

Irene Gummerson, Moss Pharmacy, Wakefield, is a pharmacist with a specialist interest in diabetes. She pointed out that pharmacists could help patients who were not achieving appropriate lipid levels.

“It is important to reinforce advice and remove misconceptions around use of statins,” she said. One misconception some patients have is that if they make improvements to their diet then they do not need to continue taking a statin.

She added that concordance with treatment was also important. “Locally, 7 per cent of drugs brought back to pharmacies have been found to be statins.” In response, a leaflet is being designed by Mrs Gummerson’s primary care trust to help educate patients about use of statins.

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