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PJ Online homeThe Pharmaceutical Journal
Vol 272 No 7298 p564
8 May 2004

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Focus on blockbusters creates opportunities for small companies

Opportunities for smaller pharmaceutical companies to build portfolios of niche medicines are opening up as a result of the pursuit of blockbuster drugs by the major multinational pharmaceutical companies.

In a statement, John Morris, global head of pharmaceuticals at management consultants KPMG said: “Major pharmaceutical companies have invested their efforts in developing blockbuster drugs and have not put as much sales and marketing effort behind smaller, existing products. That has created a tremendous opportunity for smaller drug and biotech firms to benefit from these niche drugs.”

One example is the acquisition by US King Pharmaceuticals of the American rights to two medicines, and a sales force of 375, from the Irish Elan Corporation for $750m. The two medicines — Sonata (zaleplon), a hypnotic, and Skelaxin (metaxalone), a 40-year-old muscle relaxant — had combined sales of $238m in the US in 2002.

Similarly, Shire Pharmaceuticals recently paid $31m to acquire the patent rights to Fosrenol (lanthanum carbonate), which reduces high blood phosphate levels in end-stage renal failure. Such acquisitions enable smaller and middle-market pharmaceutical companies to build a portfolio of established drugs and to generate sufficient sales to fund new drug research.

Mr Morris said: “There is now a large range of products which is no longer of interest to big pharma. Those drugs simply fall below their threshold. However, there are now plenty of companies which are more than comfortable with drugs generating $200m to $400m a year.”

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