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Vol 273 No 7306 p20
3 July 2004

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Statins

Marketing or patient empowerment?

From Mr J. H. A. J. Durodie, MRPharmS

The response by Stephen Mann and Jeremy Cottrell (PJ, 26 June, p804) brings up some important issues. They state that “extrapolation ... can be undertaken with considerable confidence”. No true science can be based on extrapolated results: such results may be valid but need to be treated with caution as opposed to “considerable confidence”. This simply re-affirms the paucity of firm evidence.

They further question whether considering number needed to treat (NNT) is appropriate for over-the-counter sales — I would dare to dispute that, unless we believe that the punters can get anything so long as they pay for it. In a case where community pharmacists will need, and be expected, to make an assessment before a sale together with providing appropriate advice and counselling about the use of an OTC medicine, NNT has to be part of the knowledge base drawn upon before that sale. The reality is that with a NNT of 71 (see PJ, 5 June, p706) this does not bode well for the individual patient — I just hope my neighbour is not relying on the same odds lest I help him benefit at my cost. Furthermore, bearing in mind that for any long-term medication compliance falls to abysmal levels after about two years, the likelihood of “customers” continuing with simvastatin 10mg for any meaningful period is debatable, despite the fact that this is what they would need to do.

I am convinced that over £150 per annum spent on lifestyle, notably dietary, improvement would give customers a far better overall health return for their money than committing themselves to long-term medication and its associated interactions and adverse effects.

I am grateful to Peter Burrill (PJ, 29 May, p670) and David Phizackerley (PJ, 5 June, p706) for highlighting some of the not insubstantial issues related to this POM-to-P move and would urge all community pharmacists to find out about the evidence (from sources over and beyond that provided by the marketing representatives) so as to be clear what advice they offer customers seeking to purchase simvastatin 10mg.

This matter does not lead to a “resounding yes” as Johnson & Johnson would have us believe. It may well, however, become a postcode money-spinner at the expense of the “worried well”.

The Government is encouraging our public health role: so, please, think twice before enabling “customers” to “swallow the tablets” — hook, line and sinker!

J. Durodie
Redhill, Surrey

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