Treasures of the Royal Pharmaceutical Society’s Collections
Pharmacopoeia Londinensis 1618 (the London pharmacopoeia)
The project to produce a pharmacopoeia for all London apothecaries was first raised by the Royal College of Physicians in 1585. Although there are further occasional references to it in the archives of the Royal College it is not until 1614 that progress appeared to have been made and, by 1617 the pharmacopoeia was "on the point of completion".
The Pharmacopoeia Londinensis appeared on 7 May 1618 with a dedication
by the royal physician Sir Theodore Turguet de Mayerne and a preface
that refers to the work as a formulary for the citizens of London. However,
it was a Royal Proclamation that led to it becoming recognised as Europe's
first national pharmacopoeia. The proclamation declared the pharmacopoeia
to apply to "all and singular apothecaries of this our Realme of
England or the dominions thereof".
The pharmacopoeia contains 712 compound remedies arranged by class into
waters, ointments, lozenges, etc. At the rear there is a list of 680
crude drugs used in these remedies. The list of crude drugs is arranged
by origin into plants (roots, leaves, etc), animals and animal parts,
salts and metals. The sources for the formulae in the pharmacopoeia were
varied and included Galen and Avicenna as well as members of the Royal
College including Turguet de Mayerne.
Despite the claim on publication that the pharmacopoeia was "now
perfected" it was withdrawn within a few months. The official reason
given by the Royal Society of Physicians was that it had been produced
without authorisation by an over eager printer. This explanation has
been challenged by historians ever since and comparison of the May edition
with the December replacement seems to suggest more fundamental changes
than just to correct a printer's error.
The replacement for the withdrawn May 1618 edition appeared in December
of the same year. The new edition contained 963 compound remedies compared
to 712 in the earlier version and 1,190 crude drugs instead of the 680
in May. In addition the list of crude drugs was moved from the back to
the front.
This, in addition to other changes, has led some historians to argue
that the two versions are fundamentally different and that the withdrawal
of the May edition was not down solely to an over enthusiastic printer.
Indeed one historian, the American George Urdang, has gone as far as
to argue that the changes between the May and December versions were
the result of a power struggle within the Royal College with the younger
members gaining the upper hand. Another suggestion is that the earlier
version was rushed out to help with trade protection. Whatever the truth,
the December version is regarded as the true “first” edition
and, as Melvin Earles says, is "the basis for the official English
materia medica until the reforms of the 18th century".
The frontispiece shown here is from the December 1618 edition held in
the Society's library.
The library holds over 60,000 books. Many such as this treasure cover
the origins of pharmacy. A contemporary collection covers all aspects
of pharmacy, pharmacy practice, and related subjects. The collection
can be searched on the online
catalogue and
many items are available for loan to members.
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