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Vol 273 No 7317 p375
18 September 2004

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Fitness, not fatness, predicts heart disease

Fitness may be a better predictor of heart disease than fatness in women, a new study suggests.

The US research, involving some 900 women having angiography for suspected ischaemia, found that those with higher levels of fitness had a lower risk of actual heart disease than those who were less fit. In contrast, body mass index and fat distribution were not associated with the risk of cardiovascular disease in this study.

Although the authors point out that their data on fitness were collected from simple, self-reported questionnaires, they add that the findings support previous work (JAMA 2004;292:1179-87).
In contrast, a prospective cohort study of almost 38,000 healthy women found that body mass index predicted the development of diabetes better than physical activity. The authors say: “These findings underscore the critical importance of adiposity as a determinant of diabetes” (JAMA 2004;292:1188-94).

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