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PJ Online homeThe Pharmaceutical Journal
Vol 273 No 7323 p635
30 October 2004

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Smokers are more likely to develop asthma

Former and current smokers are more likely to develop asthma than those who have never smoked, researchers have found.

They compared the smoking habits of 521 newly identified asthma cases and 932 randomly selected controls from an area in Southern Finland during a two-and-a-half-year case-control study.

The risk of developing asthma was higher among current smokers (adjusted odds ratio 1.33, 95 per cent confidence interval 1.00–1.77) and former smokers, (1.49, 1.12–1.97) than among those who had never smoked. People who smoked one to 14 cigarettes per day were found to have a greater risk of developing asthma than those who only smoked occasionally (1.93, 1.26–2.95 versus 1.25, 0.76–2.06). Unexpectedly, the risk appeared to be lower among those who smoked 15 cigarettes per day or more (1.05, 0.71–1.56).

The researchers were surprised by this finding and suggest that smokers might have changed their smoking habits because of respiratory symptoms they experienced before asthma was diagnosed.

The researchers also identified individuals who smoked heavily without developing asthma, and who may therefore be less susceptible to the effects of tobacco smoke. The researchers say that genetic or other susceptibility factors may account for the contradictory results that have been reported in previous studies on smoking and asthma (European Respiratory Journal 2004;24:734).

Miriam Armstrong, chief executive of PharmacyHealthLink, told The Journal that the charity is pushing for action from central Government over the health hazards posed by smoking. “This new study from Finland must help to strengthen our case and we hope that the Government will take the opportunity in the [forthcoming White Paper on public health] to state a clear commitment to protect all members of the public from second-hand smoke by announcing the introduction of smoke-free workplaces and smoke-free enclosed public places,” she said.

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