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Vol 274 No 7334 p105
29 January 2005

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Call for end to prescribing variations for cancer drugs

The All-Party Public Accounts Committee has recommended that a deadline be set for ending the current wide variations in prescribing of anti-cancer drugs, such as trastuzumab (Herceptin).

Their inquiry (PDF 1.1MB) into regional inequalities in cancer mortality rates found that such drugs, which can roughly double the survival time for women with advanced breast cancer, were prescribed less often in deprived parts of the north of England. Local NHS cancer networks reported that “uneven availability is not due to problems in getting funding for drug purchases, but rather to lack of specialist staff and unsuitable pharmacy accommodation, and variations in clinical practice in the prescribing of approved drugs, leading to local variations in the implementation of National Institute for Clinical Excellence guidelines.”

The PAC concluded: “The recommendations of the national cancer director regarding resources, clinical practices and enhancements in NICE guidance should be implemented speedily, with a clear timetable for monitoring their impact and reviews of progress.”

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