The
Pharmaceutical Journal
Vol 274 No 7336 p171
12 February 2005
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New drug beats Glivec resistanceScientists have developed a compound, called ONO12380, that may overcome the problem of imatinib (Glivec) resistance in patients with chronic myelogenous leukaemias. The compound targets a different site of the tyrosine kinase to imatinib (Proceedings of the National Academy of Sciences early online edition) |