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Vol 274 No 7337 p199
19 February 2005

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Better results for STIs if patients offered treatment for partners

Recurrence of sexually transmitted infections can be reduced by giving patients medicines to take home for their partners, new research suggests.

US researchers randomised almost 2,000 patients with chlamydia or gonorrhoea to receive either a standard or an enhanced referral service for their partners. Patients in the standard group were advised to refer their partners for treatment and were offered help with telling their partners about the infection. In the enhanced group, patients were offered medicine to take home to give to their partners, or the option for a member of medical staff to contact the partners and provide them with treatment without an examination.

The researchers found that persistent or recurrent gonorrhoea occurred in 121 out of 931 patients receiving standard referral advice (13 per cent), compared with 92 out of 929 patients receiving the enhanced referral service (10 per cent). The reduction was greater for gonorrhoea than for chlamydia infections.

The researchers suggest that “patient-delivered partner therapy” should be incorporated into clinical treatment programmes, but acknowledge the potential risks involved.

These include the possibility of a partner having an allergic reaction to the treatment, partners being infected with other concurrent diseases that would only be identifiable upon examination and the loss of the opportunity to counsel partners for the need to refer, in turn, any other sexual partners they may have (New England Journal of Medicine 2005;352:676).

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