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Vol 274 No 7339 p258
5 March 2005

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Pharmacists to be called upon during flu pandemic

Flu vaccine production

Flu vaccine production will be stepped up if a pandemic strain emerges

Pharmacists may have a key role to play in administering any new vaccine that becomes available during an influenza pandemic, a Government report confirmed this week.

Pharmacists may also be recruited to treat patients, according to the UK Influenza Pandemic Contingency Plan published earlier this week by the Department of Health.

The report, which was released jointly by Health Secretary John Reid and England’s chief medical officer, Sir Liam Donaldson, said it would “explore” these options as part of the health service response to mass flu vaccine immunisation.

Dr Reid also announced that stockpiles of 14.6 million courses of the antiviral oseltamivir (Tamiflu) are being prepared —enough to treat 25 per cent of the population — in line with World Health Organization recommendations.

Pharmaceutical company Roche has been contracted to supply 7.3 million courses by the end of the next financial year with the remainder available as soon as possible after that date.

The antiviral will not be effective in stopping the spread of any new flu strain (which is expected to be avian flu). It is, however, likely to help reduce complications of infection and reduce the severity of symptoms. But the Government admits that it will take time, possibly up to eight months following the first outbreak, to develop a suitable vaccine to beat any new strain of flu.

Professor Donaldson said: “We have already started work which should help speed up the production of a vaccine, once a pandemic strain of flu has emerged. The announcement of the procurement of a large stock of antiviral drugs will give us another potentially valuable counter measure.”

The Government expects to make use of NHS Direct during any pandemic and its online version will provide information to help answer the public’s questions. Regular advice for health professionals, including pharmacists, will be available on the CMO, DoH and HPA web sites. The DoH will also rely on its existing information cascade system to communicate with the NHS and it will lead on the purchase and supply of any vaccine on behalf of all UK countries, the report confirmed.

The report predicts a pandemic could result in at least 50,000 UK deaths.

The plan, which updates the last one published eight years ago, follows a warning last week from the World Health Organization of a possible avian flu pandemic. The WHO urged governments in Asia — which has so far reported 55 human cases of avian flu of which 42 have been fatal — as well as governments across the world to invest money in anti-avian flu measures.

Chiron licence restored Flu vaccine manufacturer Chiron has had its manufacturing licence suspension lifted. The Medicines and Healthcare products Regulatory Agency suspended the company’s licence in October last year after it failed to comply with good manufacturing practice. The company has now met MHRA requirements and is able to recommence production of Fluvirin.

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