The Pharmaceutical Journal
Vol 274 No 7344 p412
9 April 2005

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Diuretics first line

Diuretics should be used first line for both black and non-black patients with high blood pressure, data from the ALLHAT study show. The analysis was conducted to determine whether an angiotensin converting enzyme inhibitor or calcium channel blocker is superior to a thiazide diuretic in reducing cardiovascular disease incidence in racial subgroups (JAMA 2005;293:1595).