The Pharmaceutical Journal
Vol 274 No 7349 p574
14 May 2005

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Amiodarone vs sotalol in AF

Amiodarone and sotalol convert atrial fibrillation to sinus rhythm equally effectively, say researchers. Amiodarone is superior in terms of maintaining sinus rhythm overall, but both drugs have similar efficacy in patients with ischaemic heart disease (New England Journal of Medicine 2005;352:1861).