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PJ Online homeThe Pharmaceutical Journal
Vol 274 No 7350 p611
21 May 2005

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Letters to the Editor

MRSA

Work being done with bacteriophages

From Mr A. Fairhead

In the article “Understanding antibiotic resistance” (PJ, 23 April, p501) no mention was made of the work being done with bacteriophages. A Google search on “MRSA bacteriophage” gives a large number of references, including work being carried out at the University of Strathclyde.

Is it not time more resource was put into this proven yet largely unused technique?

Adrian Fairhead
Eastbourne, Brighton

 

HAYLEY WICKENS and PAUL WADE, authors of the article, respond:

Thank you for your observation concerning the potential use of bacteriophages in multi-drug resistant infection. Although we are aware of past, uncontrolled (but promising) work in Eastern Europe, the utility of phage therapy in plant and animal settings, and the ongoing research into human applications of phage therapy, both the remit of our article and the still experimental nature of phage research led us to omit this topic.

There is growing interest from researchers in this area, and many of the initial drawbacks of phage therapy are being addressed, with potentially exciting results being achieved.

Should we be commissioned to revisit this area in the future, the increasing focus on phage therapy worldwide (including in the UK) is likely to ensure that this topic will be covered in significantly more detail.

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