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PJ Online homeThe Pharmaceutical Journal
Vol 275 No 7357 p40
9 July 2005

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WHO calls for adequate vitamin D supplementation

More aggressive supplementation with vitamin D is needed for post-menopausal women with osteoporosis, according to a review conducted by the World Health Organization and presented at a recent meeting on bone health.

Jean-Yves Reginster, director of the WHO collaborating centre for public health aspects in rheumatic disease, presented results from the review at a joint meeting of the European Calcified Tissue Society and International Bone and Mineral Society in Geneva last month. He reported that 97 per cent of fracture sufferers admitted to hospital have inadequate levels of vitamin D and that 52 per cent of women with osteoporosis in Europe have levels of serum 25-hydroxyvitamin D3 below 30ng/ml3. Despite these sub-optimal levels, fewer than one in five (17.6 per cent) women with osteoporosis currently receive vitamin D supplementation.

Commenting on the data, David Hosking, City Hospital, Nottingham, said: “Most UK specialists will be unsurprised by these WHO data. We have recognised for some time that our patients’ vitamin D uptake is inadequate and, recently, several large, UK-specific trials have reinforced this view.”

He added that compliance with treatment is also known to be a problem. “In practice, it is often the patients who need supplementation least who adhere best to their treatment. The issue of compliance in the highest-risk individuals may therefore be even more poignant.”

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