The Pharmaceutical Journal
Vol 275 No 7361 p158
6 August 2005

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Modafinil for sleep disorder

Modafinil is of some value in treating shift-work sleep disorder but does not restore sleepiness to normal levels (New England Journal of Medicine 2005;353:476). In 209 patients modafinil 200mg taken before a night shift improved symptoms of sleepiness as well as objective measures of sleep propensity and performance compared with placebo.