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The Pharmaceutical Journal
Vol 275 No 7366 p315
10 September 2005

Books

New edition even more helpful in assisting with preparation of “specials”

Trissel’s stability of compounded formulations’ (3rd edition), Lawrence A. Trissel. Pp xi+496. Price $99.95. Washington DC: American Pharmaceutical Association; 2005. ISBN 1 58212 067 6


This book is an attempt to present a precise, ready reference source for stability of compounded formulations. It is an improvement on the previous two editions and also contains an additional two useful appendices.

Prescriptions for extemporaneously prepared medicines (“specials”) which pharmacists are asked to supply do not appear to be decreasing. The most frequently asked questions are, “Can we make a liquid form of this?” and “What is the shelf life?” Although not the only source of information, ‘Trissel’s stability of compounded formulations’ is an essential book that will provide many of the answers to these questions.

The second edition is a well-thumbed book on my shelf and this third edition is a much needed update. It contains updated monographs on 355 products, an increase of over 75, arranged alphabetically by non-proprietary name. Each monograph is organised into three easy-to-use categories: “properties”, “general stability” and “stability” reports of the compounded preparations. A fourth category, “Compatibility with other drug products” is included where information is available.

Two new useful appendices have been added: “Beyond-use dating for non-sterile compounded preparations and “Beyond-use dating for sterile compounded preparations”.

There is an index of non-proprietary and branded names.

This book is a valuable resource to support the “special needs of the patient”.


Colin Ranshaw (principal pharmacist quality assurance and control at St Mary's Pharmaceutical Unit, Cardiff)

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