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PJ Online homeThe Pharmaceutical Journal
Vol 275 No 7367 p330
17 September 2005

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Global type 2 diabetes guidelines launched

Global guidelines for the treatment of patients with type 2 diabetes, were launched by the International Diabetes Federation this week.

The IDF recommends that people with type 2 diabetes should be advised that lifestyle modification can control many of the condition’s risk factors. If lifestyle interventions are insufficient to control blood glucose levels, sulfonylureas should be first-line treatment in those who are not overweight, and metformin in those who are, unless there is risk of renal impairment. The dose of metformin should be gradually increased during the early weeks to minimise the risk of gastrointestinal intolerance leading to discontinuation of treatment.

The guidelines recommend that until blood glucose levels are controlled, treatment should progress from metformin to sulfonylureas to thiazolidinedione to insulin.

The IDF also recommends that all those with type 2 diabetes who are aged over 40, or who have cardiovascular disease, should be given a standard dose statin and those with evidence of cardiovascular risk should take 75–100mg aspirin a day. In addition, HbA1c levels should be monitored every two to six months and self-monitoring of blood glucose should be available for all those newly diagnosed.

The guideline is available from the IDF website.

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