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PJ Online homeThe Pharmaceutical Journal
Vol 275 No 7372 p506
22 October 2005

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Docetaxel accepted by SMC for use within NHS Scotland

Docetaxel (Taxotere) has been accepted for use as a breast cancer treatment within NHS Scotland, the Scottish Medicines Consortium announced last week.

It is approved for use in combination with doxorubicin and cyclophosphamide for the treatment of operable breast cancer that is also present in the lymph nodes after surgery.

The SMC has also decided that patients with endometriosis who would benefit from reduced frequency of triptorelin administration can now receive a 11.25mg injection every three months (Decapeptyl SR), rather than a 3mg injection every four weeks (Decapeptyl).

It also accepts that at-risk patients with essential thrombocythaemia who do not tolerate, or whose platelet counts are not reduced to an acceptable level by, their current treatment can now receive anagrelide (Xagrid).

In addition, the SMC has accepted atorvastatin (Lipitor) and infliximab (Remicade) for restricted use. Atorvastatin’s use in supporting diet to reduce elevated total cholesterol is restricted to initiation by paediatricians or physicians specialising in the management of lipid disorders. Infliximab’s use in the treatment of ankylosing spondylitis is restricted to use in accordance with British Society of Rheumatology guidelines of July 2004.

However, cetuximab (Erbitux) for colorectal cancer, bemiparin (Zibor) for prevention or treatment of thromboembolism and glyceryl trinitrate ointment (Rectogesic) for chronic anal fissure have all been rejected for use within NHS Scotland.

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