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PJ Online homeThe Pharmaceutical Journal
Vol 276 No 7388 p195
18 February 2006

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Health of a generation to be investigated

Genetic influences on disease

Genetic influences on disease and response to treatment will be studied

Generation Scotland, a large study to investigate the influence of genetics and lifestyle on disease and response to treatment, started last week.

Researchers are planning to recruit 50,000 Scottish volunteers to the study. The aim is to help identify groups of people at high risk of developing heart disease, osteoporosis and mental illness. “We can also discover which groups of the population respond best to which medicines, enabling us to target those resources more effectively, making sure that the right patients get the right treatment,” said health minister Andy Kerr.

The Generation Scotland study will be initially recruiting patients aged 35–55 years, along with their families, through GPs. Participants will be asked to provide blood and urine samples, along with details of their lifestyle and medical history. The health of the family will be traced over 10 to 30 years.

The study is being run by the universities of Aberdeen, Dundee, Edinburgh and Glasgow, and NHS Scotland. It is being funded by a £4.4m grant from the Scottish Executive.

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