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PJ Online homeThe Pharmaceutical Journal
Vol 276 No 7388 p195
18 February 2006

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SSRIs still prescribed for children despite warnings

In 2004, 85,251 child prescriptions were issued for selective serotonin reuptake inhibitors that the Medicines and Healthcare products Regulatory Agency ruled the year before should not be given to children.

The total amounted to one in three of all antidepressants issued to juveniles, Paul Burstow (Lib Dem, Sutton and Cheam) was told in a Parliamentary written reply made by the Department of Health.

More than 6,000 of the prescriptions were for paroxetine, a drug which the MHRA had judged to be safe only for adults and should not be given to under-18s. But such rulings are not binding on GPs, who are free to use their own discretion when prescribing.

Over 27,000 prescriptions for SSRIs, including paroxetine, were written for children under 18. The MHRA in 2004 issued revised guidelines saying that only fluoxetine was safe for juveniles and even that should only be prescribed as a last resort.

Mr Burstow said: “There has been long-standing under-investment in child and adolescent mental health and the admitted levels of prescribing SSRIs to youngsters is a direct consequence of that. There should be more emphasis on therapy and less on prescribing drugs which can increase the risk of emotional distress, self-harm and even suicidal tendencies.”

He pointed to recent research that suggested that eight out of 10 GPs themselves believe that too many SSRI prescriptions are issued to both children and adults.

A DoH spokesman said: “Not all SSRIs issued to under-18s are for the treatment of depression. A proportion are for phobic states, bed-wetting and other disorders.”

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