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The Pharmaceutical Journal
Vol 276 No 7396 p451
15 April 2006

Books

Updated handbook — useful in palliative care

The syringe driver: continuous subcutaneous infusions in palliative care’ (2nd edition), by Andrew Dickman, Jennifer Schneider and James Varga. Pp vi+327. Price £24.95. Oxford: OUP; 2005. ISBN 0 19 856693X


This pocket-sized reference book is a practical resource for palliative care generalists and specialists and is available at an affordable price. The book gathers together information on continuous subcutaneous infusions, the operation of syringe drivers, symptom control and palliative care, syringe-driver medicines.

This, second edition, includes a greatly expanded section on drug compatibility, additional referenced drug monographs and details of newer syringe-driver devices.

The information in the first chapter on infusion-site reactions and the discussion of potential outcomes when medicines are mixed in a syringe, is particularly helpful to those pharmacists working in palliative care who are frequently asked about these issues.

The compatibility data tables in the final section contain an extensive list of physical and chemical stability data relating to two-, three-, four- and five-drug combinations in a single syringe. This information comes from referenced stability studies and from the clinical observations of the authors. This is possibly the most useful section of the book as data of this sort is difficult to find. The authors note that the physical stability data can only serve as an indicator of stability and may not apply in all situations. Regular checking of any unfamiliar subcutaneous syringe-driver combinations while in use is advisable.

I recommend this handbook for pharmacists working in any care setting where syringe drivers are used for symptom control.


Dorothy McArthur (is a clinical pharmacist working in palliative care at Marie Curie Hospice and St Columba’s Hospice, Edinburgh)

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