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Vol 276 No 7399 p536-538
6 May 2006

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Original papers

A pilot study assessing the effectiveness of a decision aid on patient adherence with oral bisphosphonate medication

By Sue Oakley and Tom Walley


Sue Oakley, MSc, MRPharmS, is pharmaceutical adviser to Poole Primary Care Trust, Westover House, West Quay Road, Poole Dorset BH15 1JF.

Tom Walley, MD, FRCP, is professor of clinical pharmacology at the University of Liverpool.

Correspondence to Ms Oakley
e-mail sue.oakley@poole-pct.nhs.uk

Abstract

Aim
To assess the effect of a decision aid on adherence with oral bisphosphonate medication prescribed to prevent osteoporotic fracture.

Design
Randomised controlled trial.

Subjects and setting
Postmenopausal women either with a diagnosis of osteoporosis or aged over 65 years with radiological evidence of fragility fracture, prescribed oral bisphosphonate medication, in one practice in Dorset.

Results
110 women meeting the criteria for inclusion were invited to participate; 33 were recruited and randomised. There was no statistically significant change in adherence over the course of the study (P=0.47), and changes in adherence did not differ between the 2 groups (P=0.80 Mann Whitney U test).

Conclusions
The decision aid improved participants’ ability to make a decision about which treatment was best and allowed them to discuss their medication with the GP, but it had no obvious effect on adherence when compared with the control group.

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